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December 2025 HIV Surveillance Update Report

Statewide and County Specific HIV and AIDS Incidence and Prevalence Update, December 2025

HIV Incident Cases

County Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 HIV Diagnosis Rate

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

"2018-2025 HIV Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Cook County Breakdown

Health Department Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018

Chicago Health Dept.

474

5454

Cook Co. Health Dept.

188

1750

Evanston Health Dept.

<10

50

Oak Park Health Dept.

<10

30

Skokie Health Dept.

<10

37

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

St. Clair County Breakdown

Health Department Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018

East Side Health District

<10

29

St. Clair Co. Health Dept.

26

235

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

AIDS Cases

County Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 AIDS Diagnosis Rate

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

"2018-2025 AIDS Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Cook County Breakdown

Health Department Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018

Chicago Health Dept.

257

2274

Cook Co. Health Dept.

83

684

Evanston Health Dept.

<10

23

Oak Park Health Dept.

<10

16

Skokie Health Dept.

0

12

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

St. Clair County Breakdown

Health Department Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018

East Side Health District

<10

11

St. Clair Co. Health Dept.

15

100

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025-December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018-December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

HIV (non-AIDS) and AIDS Cases Living as of 12/31/2025

County HIV (non-AIDS) Cases Living as of 12/31/2025 AIDS Cases Living as of 12/31/2025

"HIV (non-AIDS) Cases Living as of 21/31/2025" and "AIDS Cases Living as of 12/31/2025" include all living cases as of December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Cook County Breakdown

Health Department HIV (non-AIDS) Cases Living as of 12/31/2025 AIDS Cases Living as of 12/31/2025

Chicago Health Dept.

13992

11376

Cook Co. Health Dept.

3009

2617

Evanston Health Dept.

120

131

Oak Park Health Dept.

99

123

Skokie Health Dept.

53

49

"HIV (non-AIDS) Cases Living as of 21/31/2025" and "AIDS Cases Living as of 12/31/2025" include all living cases as of December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

St. Clair County Breakdown

Health Department HIV (non-AIDS) Cases Living as of 12/31/2025 AIDS Cases Living as of 12/31/2025

East Side Health District

72

56

St. Clair Co. Health Dept.

455

326

"HIV (non-AIDS) Cases Living as of 21/31/2025" and "AIDS Cases Living as of 12/31/2025" include all living cases as of December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

HIV and AIDS Demographics and Behavioral Characteristics – Illinois (Cumulative Cases)

Demographic and Behavioral Characteristics Among HIV Incident Cases Diagnosed Since 2018 – Illinois

Race/Ethnicity

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Case Rate Total Deaths Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Total Cases", "Male Cases", and "Female Cases" includes all cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Age at Diagnosis

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Case Rate Total Deaths Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Total Cases", "Male Cases", and "Female Cases" includes all cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Mode of Exposure

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Total Deaths Male Cases Percent of Male Cases Female Cases Percent of Female Cases

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Total Cases", "Male Cases", and "Female Cases" includes all cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Demographic and Behavioral Characteristics Among AIDS Cases Diagnosed Since 2018 – Illinois

Race/Ethnicity

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Case Rate Total Deaths Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all AIDS cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Age at Diagnosis

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Case Rate Total Deaths Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all AIDS cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Mode of Exposure

Cumulative Cases Diagnosed Since 2018 Total Cases Percent of Total Cases Total Deaths Male Cases Percent of Male Cases Female Cases Percent of Female Cases

"Total Cases", "Male Cases", and "Female Cases" includes all AIDS cases diagnosed and reported since January 1, 2018

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Total Deaths" refers to the number of deaths among cases diagnosed since January 1, 2018

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

HIV and AIDS Demographics and Behavioral Characteristics – Illinois (Living Cases)

Demographic and Behavioral Characteristics Among Living HIV (non-AIDS) Cases – Illinois

Race/Ethnicity

Living Cases Total Cases Percent of Total Cases Case Rate Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all living HIV (non-AIDS) cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Living cases (as of December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used)

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Age at Report

Living Cases Total Cases Percent of Total Cases Case Rate Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all living HIV (non-AIDS) cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Living cases (as of December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used)

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Mode of Exposure

Living Cases Total Cases Percent of Total Cases Male Cases Percent of Male Cases Female Cases Percent of Female Cases

"Total Cases", "Male Cases", and "Female Cases" includes all living HIV (non-AIDS) cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Demographic and Behavioral Characteristics Among Living AIDS Cases – Illinois

Race/Ethnicity

Living Cases Total Cases Percent of Total Cases Case Rate Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all living AIDS cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Living cases (as of December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used)

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Age at Report

Living Cases Total Cases Percent of Total Cases Case Rate Male Cases Percent of Male Cases Male Case Rate Female Cases Percent of Female Cases Female Case Rate

"Total Cases", "Male Cases", and "Female Cases" includes all living AIDS cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

"Case Rate", "Male Case Rate", and "Female Case Rate" = Living cases (as of December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used)

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Mode of Exposure

Living Cases Total Cases Percent of Total Cases Male Cases Percent of Male Cases Female Cases Percent of Female Cases

"Total Cases", "Male Cases", and "Female Cases" includes all living AIDS cases as of December 31, 2025

"Percent of Total Cases", "Percent of Male Cases", and "Percent of Female Cases" refers to the percent of cases falling into a specific demographic category

Totals may not add up due to missing values

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Regional HIV and AIDS Incidence and Prevalence Rates

HIV Incident Cases

Region Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 HIV Diagnosis Rate

Winnebago (Region 1) – Boone, Bureau, Carroll, DeKalb, Henry, Jo Daviess, Lee, Mercer, Ogle, Rock Island, Stephenson, Whiteside, Winnebago
Peoria (Region 2) – Fulton, Hancock, Henderson, Knox, LaSalle, Marshall, Mason, McDonough, McLean, Peoria, Putnam, Stark, Tazewell, Warren, Woodford
Sangamon (Region 3) – Adams, Brown, Cass, Christian, De Witt, Greene, Logan, Macon, Menard, Montgomery, Morgan, Moultrie, Piatt, Pike, Sangamon, Schuyler, Scott, Shelby
St. Clair (Region 4) – Bond, Calhoun, Clinton, Jersey, Macoupin, Madison, Monroe, Randolph, St. Clair, Washington, Fayette, Marion
Jackson (Region 5) – Alexander, Edwards, Franklin, Gallatin, Hamilton, Hardin, Jackson, Jefferson, Johnson, Massac, Perry, Pope, Pulaski, Saline, Union, Wabash, Wayne, White, Williamson
Champaign (Region 6) – Champaign, Clark, Clay, Coles, Crawford, Cumberland, Douglas, Edgar, Effingham, Ford, Iroquois, Jasper, Kankakee, Lawrence, Livingston, Richland, Vermilion
Collar (Region 7) – DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
Region 8 (Cook) – Suburban Cook

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025- December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018- December 31, 2025

"2018-2025 HIV Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Chicago/St. Louis EMA

Region Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 HIV Diagnosis Rate

Chicago EMA

862

8834

12.67

St. Louis EMA

50

427

8.67

Chicago EMA – Cook, DeKalb, DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
St. Louis EMA – Clinton, Jersey, Madison, Monroe, St. Clair

This category includes all new HIV diagnoses regardless of the stage of the disease [HIV (non-AIDS) or AIDS], and also is referred to as “HIV infection” or “HIV disease.”

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025- December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018- December 31, 2025

"2018-2025 HIV Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

AIDS Cases

Region Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 AIDS Diagnosis Rate

Winnebago (Region 1) – Boone, Bureau, Carroll, DeKalb, Henry, Jo Daviess, Lee, Mercer, Ogle, Rock Island, Stephenson, Whiteside, Winnebago
Peoria (Region 2) – Fulton, Hancock, Henderson, Knox, LaSalle, Marshall, Mason, McDonough, McLean, Peoria, Putnam, Stark, Tazewell, Warren, Woodford
Sangamon (Region 3) – Adams, Brown, Cass, Christian, De Witt, Greene, Logan, Macon, Menard, Montgomery, Morgan, Moultrie, Piatt, Pike, Sangamon, Schuyler, Scott, Shelby
St. Clair (Region 4) – Bond, Calhoun, Clinton, Jersey, Macoupin, Madison, Monroe, Randolph, St. Clair, Washington, Fayette, Marion
Jackson (Region 5) – Alexander, Edwards, Franklin, Gallatin, Hamilton, Hardin, Jackson, Jefferson, Johnson, Massac, Perry, Pope, Pulaski, Saline, Union, Wabash, Wayne, White, Williamson
Champaign (Region 6) – Champaign, Clark, Clay, Coles, Crawford, Cumberland, Douglas, Edgar, Effingham, Ford, Iroquois, Jasper, Kankakee, Lawrence, Livingston, Richland, Vermilion
Collar (Region 7) – DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
Region 8 (Cook) – Suburban Cook

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025- December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018- December 31, 2025

"2018-2025 AIDS Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Chicago/St. Louis EMA

Region Cases Diagnosed as of 12/31/2025 Cumulative Cases Diagnosed Since 2018 2018-2025 AIDS Diagnosis Rate

Chicago EMA

192

2036

2.92

St. Louis EMA

17

115

2.33

Chicago EMA – Cook, DeKalb, DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
St. Louis EMA – Clinton, Jersey, Madison, Monroe, St. Clair

"Cases Diagnosed as of 12/31/2025" includes cases diagnosed and reported between January 1, 2025- December 31, 2025

"Cumulative Cases Diagnosed Since 2018" includes all cases diagnosed and reported between January 1, 2018- December 31, 2025

"2018-2025 AIDS Diagnosis Rate" = Diagnosed cases (January 1, 2018- December 31, 2025)/Population*100,000 (Census July 1, 2020 population estimates were used); rates were annualized

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

HIV (non-AIDS) and AIDS Cases Living as of 12/31/2025

Region HIV (non-AIDS) Cases Living as of 12/31/2025 AIDS Cases Living as of 12/31/2025

Winnebago (Region 1) – Boone, Bureau, Carroll, DeKalb, Henry, Jo Daviess, Lee, Mercer, Ogle, Rock Island, Stephenson, Whiteside, Winnebago
Peoria (Region 2) – Fulton, Hancock, Henderson, Knox, LaSalle, Marshall, Mason, McDonough, McLean, Peoria, Putnam, Stark, Tazewell, Warren, Woodford
Sangamon (Region 3) – Adams, Brown, Cass, Christian, De Witt, Greene, Logan, Macon, Menard, Montgomery, Morgan, Moultrie, Piatt, Pike, Sangamon, Schuyler, Scott, Shelby
St. Clair (Region 4) – Bond, Calhoun, Clinton, Jersey, Macoupin, Madison, Monroe, Randolph, St. Clair, Washington, Fayette, Marion
Jackson (Region 5) – Alexander, Edwards, Franklin, Gallatin, Hamilton, Hardin, Jackson, Jefferson, Johnson, Massac, Perry, Pope, Pulaski, Saline, Union, Wabash, Wayne, White, Williamson
Champaign (Region 6) – Champaign, Clark, Clay, Coles, Crawford, Cumberland, Douglas, Edgar, Effingham, Ford, Iroquois, Jasper, Kankakee, Lawrence, Livingston, Richland, Vermilion
Collar (Region 7) – DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
Region 8 (Cook) – Suburban Cook

"HIV (non-AIDS) Cases Living as of 12/31/2025" and "AIDS Cases Living as of 12/31/2025" include all living cases as of December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.

Chicago/St. Louis EMA

Region HIV (non-AIDS) Cases Living as of 12/31/2025 AIDS Cases Living as of 12/31/2025

Chicago EMA

19908

14704

St. Louis EMA

804

516

Chicago EMA – Cook, DeKalb, DuPage, Grundy, Kane, Kendall, Lake, McHenry, Will
St. Louis EMA – Clinton, Jersey, Madison, Monroe, St. Clair

"HIV (non-AIDS) Cases Living as of 12/31/2025" and "AIDS Cases Living as of 12/31/2025" include all living cases as of December 31, 2025

Notes: An asterisk (*) represents a value >10 that, if provided, could result in the back calculation of a cell size <10. All data are provisional and subject to change. Illinois Department of Corrections cases are included in county totals.